Host range mutants of v-src: alterations in kinase activity and substrate interactions
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چکیده
منابع مشابه
Host range mutants of v-src: alterations in kinase activity and substrate interactions.
Host range mutants of Schmidt-Ruppin v-src that transform chicken embryo fibroblasts (CEF) but not Rat-2 cells were generated previously by linker insertion-deletion mutagenesis (J. E. DeClue and G. S. Martin, J. Virol. 63:542-554, 1989). One of these mutants, SRX5, in which Tyr-416 is substituted by the sequence Ser Arg Asp, retained high levels of kinase activity in vitro and in vivo, both in...
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in cell-substratum contact sites. homologous to a v-src substrate and is located overexpressed in human carcinomas, is The product of the EMS1 gene, amplified and
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 1992
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.66.7.4315-4324.1992